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WEBbook of Biologic Therapies > Recombinant Cytokines

Recombinant Cytokines

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Chemical or Common Name Brand Name Other Names Molecular Structure Licensed Indication,
Major Target Diseases
Manufacturer and/or Distributor
Interferon alpha-2a Roferon-A Interferon alfa-2A recombinant, human

hairy cell leukemia;
chronic hepatitis C;
chronic myelogenous leukemia (Philadelphia chromosome positive, minimally pretreated)

Roche
Interferon alpha-2b
Intron A
Interferon alfa-2B
recombinant, human
hairy cell leukemia;
malignant melanoma;
follicular lymphoma;
condylomata acuminata;
AIDS-related Kaposi's sarcoma;
chronic hepatitis B;
chronic hepatitis C
Schering
Interferon beta-1a
Rebif

recombinant, human, glycosylated
relapsing forms of multiple sclerosis
EMD Serono
Pfizer
Interferon beta-1b
Betaseron

recombinant, human
relapsing forms of multiple sclerosis Bayer
Interferon gamma
Actimmune

recombinant, human
chronic granulomatous disease;
severe, malignant osteopetrosis
InterMune
Oprelvekin Neumega Interleukin-11, rhIL-11
recombinant, human IL-11 risk of, or pre-existing, severe thrombocytopenia and/or need for platelet transfusions following myelosuppressive chemotherapy in patients with nonmyeloid malignancies
Wyeth
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